Lexmark printer setup involves several essential steps to ensure a successful installation. Firstly, unpack the printer and remove all packaging materials. Attach the power supply. Next, install the ink cartridges or toner cartridges following the manufacturer's instructions. Install the printer drivers and software provided by Lexmark. Finally, run a test print to verify the setup and ensure proper functionality. Following these steps diligently will help you achieve a smooth and successful Lexmark printer setup.